Article

Screening of a chemogenetic library unveils dual-stage antimalarials with low cytotoxicity

2025-10-27

Abstract excerpt

<h4>ABSTRACT</h4> The global effort to eradicate malaria requires the development of drugs with novel mechanisms of action and differentiated pharmacological profiles. Both liver and blood phases of Plasmodium infection are essential for disease progression and transmission, making them primary targets for therapeutic intervention. In this study, we established a dual-luciferase reporter assay to simultaneously...

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Literature Corpus work: 081ce49a-7c7b-5e17-935b-b8413dcbb5b4
DOI: 10.1101/2025.10.26.684713

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