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MMV687794 blocks <i>Plasmodium falciparum</i> invasion of red blood cells by targeting a Surface-associated Lipid-Interacting Rhoptry Protein, <i>Pf</i> SLIRP

2026-02-25

Abstract excerpt

Invasion of red blood cells (RBCs) by the human malaria parasite, Plasmodium falciparum , drives disease. During invasion, the parasite pushes its way into the RBC while wrapping the RBC membrane around itself to establish the parasitophorous vacuole, a stable niche within the RBC where the parasite grows. To better understand invasion, we investigated the mechanism of action of an invasion-inhibitory compound, M...

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Literature Corpus work
d50914ed-8667-518f-a7e9-4e3e74983a27
DOI
10.64898/2026.02.24.707847
Open publication

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MMV687794 blocks <i>Plasmodium falciparum</i> invasion of red blood cells by targeting a Surface-associated Lipid-Interacting Rhoptry Protein, <i>Pf</i> SLIRPDOI 10.64898/2026.02.24.707847
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