Article

A fast-acting inhibitor of blood-stage <i>P. falciparum</i> with mechanism distinct from artemisinin and chloroquine

2024-08-12

Abstract excerpt

<h4>ABSTRACT</h4> Artemisinins are first-line treatment for malaria, prized for their extremely fast reduction of parasite load in patients. New fast-acting antimalarial compounds are urgently needed to counter artemisinin resistance, but the fast parasite reduction observed with artemisinins is rare among antimalarial compounds. Here we show that MMV1580853 has a very fast in vitro killing rate, comparable to t...

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Literature Corpus work: 052bb98d-1ddc-514a-9c2b-fd5f42293ec6
DOI: 10.1101/2024.08.12.607553

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