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Multistage and transmission-blocking tubulin targeting potent antimalarial discovered from the open access MMV Pathogen Box

2022-04-20

Abstract excerpt

<h4>ABSTRACT</h4> Development of resistance to current antimalarial therapies remains a significant source of concern. To address this risk, new drugs with novel targets in distinct developmental stages of Plasmodium parasites are required. In our current work, we have targeted P. falciparum Tubulin ( Pf Tubulin) proteins which represent some of the potential drug targets for malaria chemotherapy. Plasmodial Mi...

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Literature Corpus work
a01ebeb6-d7e8-5201-95d5-a16bab37c231
DOI
10.1101/2022.04.20.488926
Open publication

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Multistage and transmission-blocking tubulin targeting potent antimalarial discovered from the open access MMV Pathogen BoxDOI 10.1101/2022.04.20.488926
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