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Article

Intrabacterial regulation of a cytotoxic effector by its cognate metaeffector promotes <i>Legionella pneumophila</i> virulence

2022-06-12

Abstract excerpt

Legionella pneumophila is a natural pathogen of unicellular protozoa that can opportunistically infect macrophages and cause Legionnaires’ Disease. Intracellular replication is driven by hundreds of bacterial effector proteins that are translocated into infected host cells by a Dot/Icm type IV secretion system. L. pneumophila effectors are temporally regulated in part by a unique family of translocated regulatory...

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Identifiers and source

Literature Corpus work
20ede77e-f858-5250-8e8a-1adbe8a87996
DOI
10.1101/2022.06.12.495833
Open publication

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Intrabacterial regulation of a cytotoxic effector by its cognate metaeffector promotes <i>Legionella pneumophila</i> virulenceDOI 10.1101/2022.06.12.495833
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