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More than 16,000 effectors in the <i>Legionella</i> genus genome provide multiple, independent combinations for replication in human cells

2018-06-19

Abstract excerpt

<h4>Significance</h4> Legionella pneumophila is a bacterial pathogen causing outbreaks of a lethal pneumonia. The genus Legionella comprises 65 species for which aquatic amoebae are the natural reservoirs. Using functional and comparative genomics to deconstruct the entire bacterial genus we reveal the surprising parallel evolutionary trajectories that have led to the emergence of human pathogenic Legionella. A...

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Literature Corpus work
e5c934ba-a9f5-5b8c-abe8-a258b6261548
DOI
10.1101/350777
Open publication

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