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The <i>Legionella pneumophila</i> metaeffector Lpg2505 (SusF) regulates SidI-mediated translation inhibition and GDP-dependent glycosyltransferase activity

2019-11-16

Abstract excerpt

Legionella pneumophila , the etiological agent of Legionnaires Disease, employs an arsenal of hundreds of Dot/Icm-translocated effector proteins to facilitate replication within eukaryotic phagocytes. Several effectors, called metaeffectors, function regulate the activity of other Dot/Icm-translocated effectors during infection. The metaeffector Lpg2505 is essential for L. pneumophila intracellular replication on...

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Literature Corpus work
031b9c80-7174-500f-9b62-1891e36ace5a
DOI
10.1101/845313
Open publication

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