Article

The EspN transcription factor is an infection-dependent regulator of the ESX-1 system in <i>M. marinum</i>

2023-02-16

Abstract excerpt

Bacterial pathogens use protein secretion systems to translocate virulence factors into the host and to control bacterial gene expression. The ESX-1 (ESAT-6 system 1) secretion system facilitates disruption of the macrophage phagosome during infection, enabling access to the cytoplasm, and regulates widespread gene expression in the mycobacterial cell. The transcription factors contributing to the ESX-1 transcript...

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Literature Corpus work: c6d87d26-2f87-5969-8c3b-67bffabafd3a
DOI: 10.1101/2023.02.15.528779

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