Article

Fis family members synergistically control the virulence of <i>Legionella pneumophila</i>

2024-09-27

Abstract excerpt

<h4>ABSTRACT</h4> Legionella pneumophila virulence is controlled in a growth phase-dependent manner by a complex regulatory network involving several two-component systems, small regulatory RNAs and the translational CsrA regulator. Here, we address the additional role of Nucleoid-associated proteins (NAP) regulators in this network, by investigating the regulatory functions of the three Fis paralogs (Fis1, Fis2,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d1d8180f-fdfa-56ac-8a18-268e2b943977
DOI: 10.1101/2024.09.25.615009

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Fis family members synergistically control the virulence of <i>Legionella pneumophila</i>DOI 10.1101/2024.09.25.615009Read

More than 16,000 effectors in the <i>Legionella</i> genus genome provide multiple, independent combinations for replication in human cellsSemantic proximity Read

Intrabacterial regulation of a cytotoxic effector by its cognate metaeffector promotes <i>Legionella pneumophila</i> virulenceSemantic proximity Read

Lsr2, a pleiotropic regulator at the core of the infectious strategy of <i>Mycobacterium abscessus</i>Semantic proximity Read

Multiple Legionella pneumophila effector virulence phenotypes revealed through high-throughput analysis of targeted mutant libraries.Semantic proximity Read

Functional diversification despite structural congruence in the HipBST toxin-antitoxin system of <i>Legionella pneumophila</i>Semantic proximity Read

<i>Legionella pneumophila</i> CRISPR-Cas suggests recurrent encounters with <i>Gokushovirinae</i>Semantic proximity Read

The CpxRA two-component system contributes to Legionella pneumophila virulence.Semantic proximity Read

Analysis of the Legionella longbeachae Genome and Transcriptome Uncovers Unique Strategies to Cause Legionnaires' DiseaseSemantic proximity Read

SpxA1 and SpxA2 Function as a Stoichiometry-Dependent Regulatory Rheostat Governing Virulence Gene Expression in Group A StreptococcusSemantic proximity Read

Genome dynamics in Legionella: the basis of versatility and adaptation to intracellular replication.Semantic proximity Read

The <i>Legionella pneumophila</i> metaeffector Lpg2505 (SusF) regulates SidI-mediated translation inhibition and GDP-dependent glycosyltransferase activitySemantic proximity Read

Transposon-insertion sequencing in a clinical isolate of <i>Legionella pneumophila</i> identifies essential genes and determinants of natural transformationSemantic proximity Read