Article
The CpxRA two-component system contributes to Legionella pneumophila virulence.
Molecular microbiology - 1 Jun 2016
Tanner Jennifer R, Li Laam, Faucher Sébastien P, Brassinga Ann Karen C
Abstract excerpt
The bacterium Legionella pneumophila is capable of intracellular replication within freshwater protozoa as well as human macrophages, the latter of which results in the serious pneumonia Legionnaires' disease. A primary factor involved in these host cell interactions is the Dot/Icm Type IV secretion system responsible for translocating effector proteins needed to establish and maintain the bacterial replicative...
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