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Article

Legionella effectors that promote nonlytic release from protozoa.

Science (New York, N.Y.) - 27 Feb 2004

Chen John, de Felipe Karim Suwwan, Clarke Margaret, Lu Hao, Anderson O Roger, Segal Gil, Shuman Howard A

Abstract excerpt

Legionella pneumophila, the bacterial agent of legionnaires' disease, replicates intracellularly within a specialized vacuole of mammalian and protozoan host cells. Little is known about the specialized vacuole except that the Icm/Dot type IV secretion system is essential for its formation and maintenance. The Legionella genome database contains two open reading frames encoding polypeptides (LepA and LepB) with...

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Identifiers

PMID: 14988561
DOI: 10.1126/science.1094226

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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