Article

Tuneable hydrogel stiffness in a 3D <i>in vitro</i> model induces epithelial to mesenchymal transition in MCF7 but not MDA-MB-231 breast cancer cells

2023-07-03

Abstract excerpt

The study of in vitro models of breast cancer is crucial for understanding and treating the malignancy in patients, with 3D in vitro models providing researchers with more biomimetic systems to overcome limitations of current to 2D cultures and in vivo animal models. Ex vivo patient tissues have shown that malignant breast tissues are stiffer than healthy or benign tissues, and that the stiffness corresponds w...

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Literature Corpus work: 1e8d3a5b-bab7-578d-942e-57dd9af2c373
DOI: 10.1101/2023.06.29.546799

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