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Article

Distinct phenotypes of cancer cells on tissue matrix gel.

Breast cancer research : BCR - 31 Jul 2020

Ruud Kelsey F, Hiscox William C, Yu Ilhan, Chen Roland K, Li Weimin

Abstract excerpt

BACKGROUND: Breast cancer cells invading the connective tissues outside the mammary lobule or duct immerse in a reservoir of extracellular matrix (ECM) that is structurally and biochemically distinct from that of their site of origin. The ECM is a spatial network of matrix proteins, which not only provide physical support but also serve as bioactive ligands to the cells. It becomes evident that the dimensional,...

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Identifiers

PMID: 32736579
DOI: 10.1186/s13058-020-01321-7
PMCID: PMC7395363

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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