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Tunable synthetic extracellular matrices to investigate breast cancer response to biophysical and biochemical cues

8 Feb 2019

Abstract excerpt

The extracellular matrix (ECM) is thought to play a critical role in the progression of breast cancer. In this work, we have designed a photopolymerizable, biomimetic synthetic matrix for the controlled, 3D culture of breast cancer cells and, in combination with imaging and bioinformatics tools, utilized this system to investigate the breast cancer cell response to different matrix cues. Specifically,...

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PMID: 31069334
DOI: 10.1063/1.5064596

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