Article

Invasion and secondary site colonization as a function of in vitro primary tumor matrix stiffness

2022-07-23

Abstract excerpt

Increased breast tissue stiffness is correlated with breast cancer risk and invasive cancer progression. However, its role in promoting bone metastasis, which shares a large burden of breast cancer deaths, has not yet been understood. To better understand the cause-effect relationship of tissue stiffness on breast cancer’s metastatic potential, we fabricated three-dimensional (3D) models to mimic breast and bone t...

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Literature Corpus work: a6587ef1-d247-5cfb-97b6-1a1348b85985
DOI: 10.1101/2022.07.22.500985

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