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Article

Breast cancer cells mechanosensing in engineered matrices: Correlation with aggressive phenotype.

Journal of the mechanical behavior of biomedical materials - 1 Aug 2016

Li Ji, Wu Yang, Schimmel Nicholas, Al-Ameen Mohammad Ali, Ghosh Gargi

Abstract excerpt

The pathogenesis of cancer is often driven by the modulation of the tumor microenvironment. Recent reports have highlighted that the progressive stiffening of tumor matrix is crucial for malignant transformation. Though extensive work has been done analyzing the mechanotransductive signals involved in tumor progression, it is still not clear whether the stiffness induced changes in cancer cell behavior is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26874251
DOI: 10.1016/j.jmbbm.2016.01.021

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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