Article

Comprehensive synthetic genetic array analysis of alleles that interact with mutation of the <i>Saccharomyces cerevisiae</i> RecQ helicases Hrq1 and Sgs1

2020-08-28

Abstract excerpt

<h4>ABSTRACT</h4> Most eukaryotic genomes encode multiple RecQ family helicases, including five such enzymes in humans. For many years, the yeast Saccharomyces cerevisiae was considered unusual in that it only contained a single RecQ helicase, named Sgs1. However, it has recently been discovered that a second RecQ helicase, called Hrq1, resides in yeast. Both Hrq1 and Sgs1 are involved in genome integrity, funct...

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Literature Corpus work: 1e13786d-bf26-5f11-850e-c016b6aea6de
DOI: 10.1101/2020.08.28.272666

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