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Article

Maintenance of Yeast Genome Integrity by RecQ Family DNA Helicases.

Genes - 18 Feb 2020

Gupta Sonia Vidushi, Schmidt Kristina Hildegard

Abstract excerpt

With roles in DNA repair, recombination, replication and transcription, members of the RecQ DNA helicase family maintain genome integrity from bacteria to mammals. Mutations in human RecQ helicases BLM, WRN and RecQL4 cause incurable disorders characterized by genome instability, increased cancer predisposition and premature adult-onset aging. Yeast cells lacking the RecQ helicase Sgs1 share many of the cellular...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32085395
DOI: 10.3390/genes11020205
PMCID: PMC7074392

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Maintenance of Yeast Genome Integrity by RecQ Family DNA Helicases.PMID 32085395Read ↗

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Human RecQ Helicases in DNA Double-Strand Break RepairSemantic proximity Read ↗

Function of recQ family helicase in genome stability.Semantic proximity Read ↗

RecQ helicases: suppressors of tumorigenesis and premature aging.Semantic proximity Read ↗

Helicase activity is only partially required for Schizosaccharomyces pombe Rqh1p function.Semantic proximity Read ↗

An overview of RecQ helicases and related diseases.Semantic proximity Read ↗

Unique and important consequences of RECQ1 deficiency in mammalian cellsSemantic proximity Read ↗

Sgs1 function in the repair of DNA replication intermediates is separable from its role in homologous recombinational repair.Semantic proximity Read ↗

RecQ family helicases in genome stability: lessons from gene disruption studies in DT40 cells.Semantic proximity Read ↗

DNA helicases Sgs1 and BLM promote DNA double-strand break resection.Semantic proximity Read ↗

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RecQ family helicases: roles in cancer and aging.Semantic proximity Read ↗

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