Article

The genetic and physical interactomes of the <i>Saccharomyces cerevisiae</i> Hrq1 helicase

2020-08-28

Abstract excerpt

<h4>ABSTRACT</h4> The human genome encodes five RecQ helicases (RECQL1, BLM, WRN, RECQL4, and RECQL5) that participate in various processes underpinning genomic stability. Of these enzymes, the disease-associated RECQL4 is comparatively understudied due to a variety of technical challenges. However, Saccharomyces cerevisiae encodes a functional homolog of RECQL4 called Hrq1, which is more amenable to experimenta...

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Literature Corpus work: ad054fe9-084d-5ddb-bcbe-aec0ce2ddc0e
DOI: 10.1101/2020.08.28.272674

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