Article
Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae.
Genetics - 1 Jan 2001
Mullen J R, Kaliraman V, Ibrahim S S, Brill S J
Abstract excerpt
The Saccharomyces cerevisiae Sgs1 protein is a member of the RecQ family of DNA helicases and is required for genome stability, but not cell viability. To identify proteins that function in the absence of Sgs1, a synthetic-lethal screen was performed. We obtained mutations in six complementation groups that we refer to as SLX genes. Most of the SLX genes encode uncharacterized open reading frames that are...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.