Article

Machine Learning Reveals Genetic Modifiers of the Immune Microenvironment of Cancer

2022-12-15

Abstract excerpt

<h4>ABSTRACT</h4> Heritability in the immune tumor microenvironment (iTME) has been widely observed, yet remains largely uncharacterized and systematic approaches to discover germline genetic modifiers of the iTME still being established. Here, we developed the first machine learning approach to map iTME modifiers within loci from genome-wide association studies (GWAS) for breast cancer (BrCa) incidence and outco...

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Literature Corpus work: 1db6d00e-f9e9-5d7d-85ec-91638d0b4826
DOI: 10.1101/2022.12.13.520300

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