Article

Targeting Germline BRCA1-Associated Breast Cancer Through Transcriptome-Guided Immunoprevention

2026-03-04

Abstract excerpt

<title>Abstract</title> <p> Women with germline <italic>BRCA1</italic> variants face a high lifetime risk of breast cancer, necessitating novel immunoprevention strategies. While the <italic>BRCA1</italic> -mutant tumor immune microenvironment (TME) is known to be immunologically active, the specific, targetable alterations that distinguish malignant tumors from the <italic>BRCA1</italic> -mutant normal ti...

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Literature Corpus work: 769f9fd9-ce6d-51f3-bcb7-392f373a7aec
DOI: 10.21203/rs.3.rs-8502955/v1

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