Article

Combinations of genomic alterations and immune microenvironmental features associate with patient survival in multiple cancer types

2024-12-27

Abstract excerpt

Oncogenesis and tumor progression are shaped by somatic alterations in the cancer genome and features of the tumor immune microenvironment (TME). How interactions of these two systems influence tumor development and clinical outcomes remains incompletely understood. To address this challenge, we developed the multi-omics analysis framework PACIFIC to systematically integrate genetic cancer drivers and infiltration...

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Literature Corpus work: fa576b09-9560-5f77-9eaf-b934264ced6b
DOI: 10.1101/2024.12.27.630504

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