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Identification of genetic determinants of breast cancer immune phenotypes by integrative genome-scale analysis

1 Feb 2017

Abstract excerpt

Cancer immunotherapy is revolutionizing the clinical management of several tumors, but has demonstrated limited activity in breast cancer. The development of more effective treatments is hindered by incomplete knowledge of the genetic determinant of immune responsiveness. To fill this gap, we mined copy number alteration, somatic mutation, and expression data from The Cancer Genome Atlas (TCGA). By using...

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PMID: 28344865
DOI: 10.1080/2162402x.2016.1253654

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