Article

Germline genetic contribution to the immune landscape of cancer

2020-01-31

Abstract excerpt

<h4>Summary</h4> The role of germline genetics in shaping the tumor immune landscape is largely unknown. Using genotypes from >9,000 individuals in The Cancer Genome Atlas, we investigated the association of common and rare variants with 139 well-defined immune traits. Our analysis of common variants identified 10 immune traits with significant heritability estimates, and an additional 23 with suggestive heritabi...

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Literature Corpus work: 400b9c1b-8a15-5c9e-931e-62050a19b850
DOI: 10.1101/2020.01.30.926527

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