Article

Platform-dependent effects of genetic variants on plasma APOL1

2025-02-02

Abstract excerpt

Mutations in apolipoprotein L1 (APOL1) are strongly associated with protection against parasitic infections and increased risk of kidney disease in individuals of African ancestry. To better understand the mechanisms underlying APOL1-related pathologies, we examined genetic drivers of circulating APOL1 in individuals of African and European ancestry from four independent cohorts (UK Biobank, AASK, deCODE, and Heal...

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Literature Corpus work: 1c773d04-fd11-5f4b-aa2d-552603ecc41e
DOI: 10.1101/2025.01.30.635763

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