Article

stAPAminer: Mining Spatial Patterns of Alternative Polyadenylation for Spatially Resolved Transcriptomic Studies

2022-07-21

Abstract excerpt

Alternative polyadenylation (APA) contributes to transcriptome complexity and gene expression regulation, which has been implicated in various cellular processes and diseases. Single-cell RNA-seq (scRNA-seq) has led to the profile of APA at the single-cell level, however, the spatial information of cells is not preserved in scRNA-seq. Alternatively, spatial transcriptomics (ST) technologies provide opportunities t...

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Literature Corpus work: aa3a1550-9405-5ec8-b04f-eb4b8976c497
DOI: 10.1101/2022.07.20.500789

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