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Article

Pairwise genetic interactions modulate lipid plasma levels and cellular uptake

2020-10-30

Abstract excerpt

<h4>SUMMARY</h4> Genetic interactions (GIs), the joint impact of different genes or variants on a phenotype, are foundational to the genetic architecture of complex traits. However, identifying GIs through human genetics is challenging since it necessitates very large population sizes, while findings from model systems not always translate to humans. Here, we combined exome-sequencing and genotyping in the UK Bio...

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Literature Corpus work
19291b55-379e-57a0-9713-fd00aa18cd41
DOI
10.1101/2020.10.29.360818
Open publication

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Pairwise genetic interactions modulate lipid plasma levels and cellular uptakeDOI 10.1101/2020.10.29.360818
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