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Genomic atlas of 7,000 plasma proteins and their associations with diseases and traits in East Asian populations

2026-02-06

Abstract excerpt

Proteogenomic studies integrating genetic, molecular, and phenotypic data have transformed target discovery, yet remain heavily biased toward European populations. Here, we present a large-scale proteogenomic atlas in a non-European population, analysing 7,289 plasma proteins profiled by SomaScan v4.1 in 3,965 Chinese adults. Genome-wide association analyses identified 3,212 protein quantitative trait loci (pQTLs)...

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Literature Corpus work
5c7bcd23-070e-58a0-9d2d-740686013de9
DOI
10.64898/2026.02.05.26345625
Open publication

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Genomic atlas of 7,000 plasma proteins and their associations with diseases and traits in East Asian populationsDOI 10.64898/2026.02.05.26345625
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