Article
Population-based genome-wide association study of plasma complex lipid species.
Nature communications - 2 May 2026
Landstra Elvire N, Imtiaz Mohammed A, Talevi Valentina, Eichelmann Fabian, Schulze Matthias B, Aziz N Ahmad, Breteler Monique M B
Abstract excerpt
The human lipidome comprises numerous complex lipids, dysregulation of which can contribute to the pathogenesis of a wide range of diseases. Despite the high heritability of parts of the lipidome, the genetic architecture of many circulating lipid species and their structure remains mostly unknown. Thus, we perform genome-wide association studies on 970 lipid species and 267 fatty acid composite measures using...
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