Article

MuVEH and mitoMuVEH improve discovery of genetic variation from single cells

2022-11-24

Abstract excerpt

Understanding the genetic underpinnings and clonal structure of malignancies at single-cell resolution is critical to accurately predicting drug response and understanding mechanisms of drug resistance and disease evolution in heterogeneous populations of cells. Here, we introduce an accessible, multiplexable, targeted mutation enrichment approach and end-to-end analysis pipeline called MuVEH (Multiplexed Variant...

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Literature Corpus work: 18766573-99a7-5a17-8f80-7eb3d811f651
DOI: 10.1101/2022.11.22.517553

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