Article

WRNIP1 prevents transcription-associated genomic instability

2023-06-24

Abstract excerpt

<h4>ABSTRACT</h4> R-loops are non-canonical DNA structures that form during transcription and play diverse roles in various physiological processes. Disruption of R-loop homeostasis can lead to genomic instability and replication impairment, contributing to several human diseases, including cancer. Although the molecular mechanisms that protect cells against such events are not fully understood, recent research h...

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Literature Corpus work: 18541628-bf57-5583-bf66-b43a9a9258bc
DOI: 10.1101/2023.06.23.546223

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