Article

Antigen-driven expansion of public clonal T cell populations in inflammatory bowel diseases

2024-05-18

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Inflammatory Bowel Diseases (IBDs), including Crohn’s disease (CD) and ulcerative colitis (UC), are known to involve shifts in the T-cell repertoires of affected individuals. These include a reduction in regulatory T cells in both diseases, increase in TNFα production in CD, expansion of an unconventional T-cell population in CD, and clonal expansion of abundant T-cell popul...

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Literature Corpus work: 17ff0924-43e1-596a-bcca-48fd72e8efc1
DOI: 10.1101/2024.05.15.594220

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