Article

Analyzing the T cell receptor repertoire of 2,804 individuals with inflammatory bowel disease identifies public T cell responses involved in the pathogenesis

2025-07-29

Abstract excerpt

Whereas altered immune processes have been identified in individuals with inflammatory bowel disease (IBD), potentially causative antigens remain to be identified. By interrogating the immune repertoire of individuals with IBD, an identification of common antigenic exposures associated with the disease can be obtained. We analyzed the T cell receptor beta (TRB) chain repertoire of 1,890 individuals with Crohn’s di...

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Literature Corpus work: 87e4e94c-13ec-50ce-8dbc-8e02f5e62184
DOI: 10.1101/2025.07.24.666514

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