Article

Shared TCRs in peripheral blood offer robust celiac disease classification independent of gluten Intake

2025-12-27

Abstract excerpt

<h4>Background and Aims</h4> Celiac disease (CeD) is a chronic digestive autoimmune disorder affecting approximately 1% of the worldwide population. It is driven by T cells activated by specific HLA-DQ2 or HLA-DQ8 molecules leading to the destruction of intestinal villi. We aimed to characterize shared CeD-specific T cells in patients on and off a gluten-free diet (GFD) from a large cohort of cases and controls....

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Literature Corpus work: bce276f4-8c3f-5bfb-bef0-785bad57f6ac
DOI: 10.64898/2025.12.26.696039

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