Article

Multi-centered T cell repertoire profiling identifies novel alterations in the immune repertoire of individuals with inflammatory bowel disease and validates previous findings

2025-05-20

Abstract excerpt

<h4>Introduction</h4> IBD is an incurable immune-mediated inflammatory disease (IMID), affecting the gut with a high rate of primary- and secondary-loss-of-response to therapy. By investigating the T cell receptor repertoire of individuals with IBD, novel therapeutic and preventive strategies can be identified, and a better understanding of IBD can be obtained. <h4>Methods</h4> Whereas most studies have so far f...

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Literature Corpus work: 7b8beac9-68c6-566b-b653-2a534b0ab154
DOI: 10.1101/2025.05.16.654339

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