Article

Divergent T Cell Phenotypes Define Pediatric Crohn’s Disease and Ulcerative Colitis

2025-10-17

Abstract excerpt

<h4>ABSTRACT</h4> Pediatric Inflammatory Bowel Disease (IBD) remains challenging to treat and difficult to prognosticate. Although multiple immune cell types coordinate pathology in both Crohn’s disease (CD) and ulcerative colitis (UC), specifying which cell types and cell states portend better or worse response to major IBD treatment strategies, including anti-TNF therapies (the only FDA-approved therapy for ped...

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Literature Corpus work: 454c90b4-ba1e-5f13-afee-1238b06f8289
DOI: 10.1101/2025.10.16.25336112

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