Article

Longitudinal T cell repertoire analysis reveals dynamic clonal T cell populations in Ulcerative Colitis

2025-01-17

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Ulcerative Colitis (UC) is characterized by chronic, relapsing and remitting inflammation in the colon and rectum. Pathogenic T cell activity is thought to play a major role in this process. T cell effector function is determined by the T cell receptor (TCR) and the antigen it recognizes. Examining the TCR repertoire can provide key insights into the adaptive immune response...

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Literature Corpus work: e7c8ebca-d9fc-5cc1-8aa0-d4b3764fd563
DOI: 10.1101/2025.01.13.632427

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