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<i>In-situ</i> Target Base Editing Combining with Biosensor-driven Strategy Reveals Critical Single Nucleotide Variants for Enhanced Recombinant Protein Secretion in <i>Pichia pastoris</i>

2026-04-10

Abstract excerpt

The disparity between the production and demand of recombinant proteins (r-proteins) has significantly hindered their commercial viability. Leveraging genomic resources offers substantial promise in enhancing our comprehension of metabolic and regulatory networks, thus facilitating the development of highly productive protein cell factories. However, the considerable gap between high-throughput strategies for moni...

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Literature Corpus work
164ddd34-2c35-514b-8afd-1657e368439e
DOI
10.64898/2026.04.09.717583
Open publication

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<i>In-situ</i> Target Base Editing Combining with Biosensor-driven Strategy Reveals Critical Single Nucleotide Variants for Enhanced Recombinant Protein Secretion in <i>Pichia pastoris</i>DOI 10.64898/2026.04.09.717583
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