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Article

Establishment of a Biosensor-based High-Throughput Screening Platform for Tryptophan Overproduction.

ACS synthetic biology - 18 Jun 2021

Liu Yongfei, Yuan Huiling, Ding Dongqin, Dong Huina, Wang Qinhong, Zhang Dawei

Abstract excerpt

With the flexibility to fold into complex structures, RNA is well-suited to act as a cellular sensor to recognize environmental fluctuations and respond to changes by regulating the corresponding genes. In this study, we established a high-throughput screening platform to screen tryptophan high-producing strains from a large repertoire of candidate strains. This platform consists of a tryptophan-specific...

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PMID: 34081459
DOI: 10.1021/acssynbio.0c00647

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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