Back to search

Article

Development of a highly efficient base editing system for <i>Lactobacilli</i> to improve probiotics and dissect essential functions

2024-08-12

Abstract excerpt

Lactobacilli play essential roles in the food industry and are increasingly explored for their potential as probiotics and therapeutic agents. Beneficial strains are primarily isolated from various natural sources including healthy human bodies, and undergo rigorous characterization and safety evaluations. Genomic and genetic information has increasingly accumulated and been linked to their various functions, to w...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
72f2ea09-cd58-5978-b772-bfa7e0f98eb3
DOI
10.1101/2024.08.12.607654
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Development of a highly efficient base editing system for <i>Lactobacilli</i> to improve probiotics and dissect essential functionsDOI 10.1101/2024.08.12.607654
Advancements in Lactiplantibacillus plantarum : probiotic characteristics, gene editing technologies and applicationsSemantic proximity
Harnessing the endogenous Type I-C CRISPR-Cas system for genome editing in <i>Bifidobacterium breve</i>Semantic proximity
Advancements in gene editing technologies for probiotic-enabled disease therapySemantic proximity
Awakening prime editing for precision engineering of probiotic <i>Escherichia coli</i> Nissle 1917Semantic proximity
Base editor-mediated large-scale screening of functional mutations in bacteria for industrial phenotypes.Semantic proximity
Progression and application of CRISPR-Cas genomic editors.Semantic proximity
One-for-all gene inactivation via PAM-independent base editing in bacteriaSemantic proximity
<i>In situ</i> targeted mutagenesis of gut bacteriaSemantic proximity
Genomic characterization of Lactobacillus fermentum DSM 20052.Semantic proximity
Multiplexed in-situ mutagenesis driven by a dCas12a-based dual-function base editor.Semantic proximity
Introduction and Perspectives of DNA Base Editors.Semantic proximity
TEM Experiment and Complete Genome Sequencing with Comparative Genomic Analysis to Uncover Potential Probiotic Features of Isolated <i>Lactobacillus delbrueckii</i> subsp. <i>indicus</i> TY-11Semantic proximity
Select a neighboring publication to make it the new centre.