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Article

AID Shapes Proliferation and Cell-of-Origin-associated Transcriptional Programs in Diffuse Large B-cell Lymphoma

2026-02-25

Abstract excerpt

<h4>ABSTRACT</h4> Activation-induced cytidine deaminase (AID), which is essential for antibody diversification, exhibits elevated expression in the activated B-cell-like (ABC) subtype of diffuse large B-cell lymphoma (DLBCL). Here, we demonstrate that AID modulates transcriptional programs linked to cell cycle progression, proliferation, and DLBCL subtype identity. AID loss in ABC-type DLBCL cell lines negatively...

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Literature Corpus work
15fc3618-a825-5155-81f8-7ba3f9114bd6
DOI
10.64898/2026.02.24.707639
Open publication

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AID Shapes Proliferation and Cell-of-Origin-associated Transcriptional Programs in Diffuse Large B-cell LymphomaDOI 10.64898/2026.02.24.707639
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