Article

Delineation of a thrombin receptor-stimulated vascular smooth muscle cell transition generating cells in the plaque-stabilising fibrous cap

2024-07-02

Abstract excerpt

<h4>Aims</h4> Vascular smooth muscle cells (VSMCs) accumulate in atherosclerotic plaques and exhibit remarkable phenotypic plasticity, contributing to both plaque growth and stability. The plaque-stabilising fibrous cap is rich in VSMC-derived cells, yet the cellular transitions and regulatory mechanisms governing fibrous cap formation remain unclear. We aimed to delineate the VSMC phenotypic transitions associat...

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Literature Corpus work: 15ca578d-03eb-5d85-b62e-f7d0c61b40d1
DOI: 10.1101/2024.07.02.600985

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