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Article

Mouse, Pig, and Human Atherosclerotic Lesions Have Common and Distinct Mesenchymal Cell Populations.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jul 2026

Sharysh Diana, Nogales Paula, Morales-Cano Daniel, Markov Anton, Izquierdo-Serrano Raúl, Carramolino Laura, Albarrán-Juárez Julián, Bentzon Jacob Fog

Abstract excerpt

BACKGROUND: Smooth muscle cell (SMC) proliferation and phenotypic transitioning drive the accumulation of a heterogeneous population of mesenchymal cells in advanced atherosclerosis, with additional contributions reported from endothelial-mesenchymal transitioning and invading adventitial cells. Animal models enable investigations of their recruitment and function, but it remains unclear to what extent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42165148
DOI: 10.1161/ATVBAHA.125.323640

Genes

DLX5
RERGL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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