Article

Molecular and spatiotemporal characterization of cells in murine atherosclerotic plaques

2024-09-08

Abstract excerpt

<h4>Objective</h4> Single-cell technologies have revolutionized our understanding of the phenotypic and transcriptional diversity of aortic leukocytes in atherosclerotic humans and mice. However, enzymatically dissociated tissues lose the spatial context of plaque cells in situ . Here we utilized imaging mass cytometry (IMC) combining with single-cell RNA sequencing (scRNA-seq) to characterize the spatial distri...

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Literature Corpus work: 084bf878-afa6-5752-94a5-c557835c00f9
DOI: 10.1101/2024.09.04.611323

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