Article

Transcriptomic, Specific Marker, and Pathway Analysis of Smooth Muscle Cell Foam Cells Relative to Macrophage Foam Cells in Human Atherosclerosis

2026-05-30

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Smooth muscle cells (SMCs) are reported to contribute the majority of cholesterol-overloaded foam cells in human and mouse atheromas. However, the transcriptome, specific markers, and biologic itinerary of SMC foam cells relative to macrophage foam cells have not been determined. <h4>METHODS</h4> Transcriptomic analysis by single cell RNA sequencing (scRNA-seq) was performe...

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Literature Corpus work: a6928a8a-83be-5d97-836d-b2605b7bd522
DOI: 10.64898/2026.05.27.728334

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