Article

CNSigs: An R Package for the Identification of Copy Number Mutational Signatures

2026-06-25

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Copy number aberrations (CNAs) are gains and losses of large genomic segments present across most cancer types and are a hallmark of cancer genomic alterations. However, the processes underlying CNAs and characteristic patterns of CNAs are poorly understood. Bioinformatic advances have identified underlying single nucleotide variant (SNV) mutational signatures resulting from...

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Literature Corpus work: 15bd327d-ebcc-5883-a1a1-a312c507caec
DOI: 10.64898/2026.06.21.733646

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