Article
Interactive analysis of large cancer copy number studies with Copy Number Explorer.
Bioinformatics (Oxford, England) - 1 Sept 2015
Newman Scott
Abstract excerpt
UNLABELLED: Copy number abnormalities (CNAs) such as somatically-acquired chromosomal deletions and duplications drive the development of cancer. As individual tumor genomes can contain tens or even hundreds of large and/or focal CNAs, a major difficulty is differentiating between important, recurrent pathogenic changes and benign changes unrelated to the subject's phenotype. Here we present Copy Number Explorer,...
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