Article

CNApp: quantification of genomic copy number alterations in cancer and integrative analysis to unravel clinical implications

2018-11-27

Abstract excerpt

<h4>ABSTRACT</h4> Somatic copy number alterations (CNAs) are a hallmark of cancer. Although CNA profiles have been established for most human tumor types, their precise role in tumorigenesis as well as their clinical and therapeutic relevance remain largely unclear. Thus, computational and statistical approaches are required to thoroughly define the interplay between CNAs and tumor phenotypes. Here we developed C...

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Literature Corpus work: b3974703-4472-5e5f-aee7-212ca19f3169
DOI: 10.1101/479667

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