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Article

CloneCNA: detecting subclonal somatic copy number alterations in heterogeneous tumor samples from whole-exome sequencing data.

BMC bioinformatics - 19 Aug 2016

Yu Zhenhua, Li Ao, Wang Minghui

Abstract excerpt

BACKGROUND: Copy number alteration is a main genetic structural variation that plays an important role in tumor initialization and progression. Accurate detection of copy number alterations is necessary for discovering cancer-causing genes. Whole-exome sequencing has become a widely used technology in the last decade for detecting various types of genomic aberrations in cancer genomes. However, there are several...

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Identifiers

PMID: 27538789
DOI: 10.1186/s12859-016-1174-7
PMCID: PMC4990858

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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